Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.
The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit https://cc.nih.gov.
Updates regarding government operating status and resumption of normal operations can be found at https://opm.gov.

Ante la falta de fondos del gobierno federal, no se actualizará este sitio web y la organización no responderá a transacciones ni consultas hasta que se aprueben los fondos.
 El Centro Clínico de los Institutos Nacionales de la Salud  (el hospital de investigación) permanecerá abierto. Consulte https://cc.nih.gov(en inglés)
Infórmese sobre el funcionamiento del gobierno federal y el reinicio de las actividades en https://opm.gov.

Year of Publication: 2013
Project: BOLD Connectivity Dynamics
FIM Authors:
Authors:
  • J. Smalt
  • J. Gonzalez-Castillo
  • T. Talavage
  • D. Pisoni
  • M. Svirsky
Abstract:

Neurobiological correlates of adaptation to spectrally degraded speech were investigated with fMRI before and after exposure to a portable real-time speech processor that implements an acoustic simulation model of a cochlear implant (CI). The speech processor, in conjunction with isolating insert earphones and a microphone to capture environment sounds, was worn by participants over a two week chronic exposure period. fMRI and behavioral speech comprehension testing were conducted before and after this two week period. After using the simulator each day for 2h, participants significantly improved in word and sentence recognition scores. fMRI shows that these improvements came accompanied by changes in patterns of neuronal activation. In particular, we found additional recruitment of visual, motor, and working memory areas after the perceptual training period. These findings suggest that the human brain is able to adapt in a short period of time to a degraded auditory signal under a natural learning environment, and gives insight on how a CI might interact with the central nervous system. This paradigm can be furthered to investigate neural correlates of new rehabilitation, training, and signal processing strategies non-invasively in normal hearing listeners to improve CI patient outcomes.


Journal: NeuroImage
Volume: 82
URL:
DOI: 10.1016/j.neuroimage.2013.06.001